{"id":3707,"date":"2021-03-09T02:40:06","date_gmt":"2021-03-09T02:40:06","guid":{"rendered":"http:\/\/saniona.com.linux18.curanetserver.dk\/san903\/"},"modified":"2023-12-14T14:25:08","modified_gmt":"2023-12-14T13:25:08","slug":"san903","status":"publish","type":"page","link":"https:\/\/saniona.com\/sv\/var-pipeline\/san903\/","title":{"rendered":"SAN903"},"content":{"rendered":"

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V\u00c5R PIPELINE<\/a><\/h6>\n

SAN903<\/p>\n<\/div>\n

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SAN903<\/h1>\n

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Precis modulering av jonkanaler f\u00f6r behandling av inflammation och fibros<\/h2>\n

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SAN903 \u00e4r en m\u00f6jlig first-in-class<\/em>-tillg\u00e5ng som h\u00e4mmar den kalciumaktiverade kaliumjonkanalen KCa3.1. Den har genomg\u00e5tt preklinisk utveckling f\u00f6r behandling av inflammatoriska och fibrotiska sjukdomar. Den nuvarande leadindikationen \u00e4r inflammatoriska tarmsjukdomar (IBD).<\/p>\n

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Hur SAN903 fungerar<\/h3>\n

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SAN903<\/strong><\/p>\n

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IMMUNCELLER OCH FIBROBLASTER<\/p>\n

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INGEN produktion av cytokin\/kollagen<\/p>\n

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INGEN celldelning eller migration<\/p>\n

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Den kalciumaktiverade kaliumkanalen KCa3.1 \u00e4r viktig f\u00f6r aktiveringen av immunceller i hj\u00e4rnan och andra v\u00e4vnader, och \u00e4r ocks\u00e5 involverad i den onormala produktion av bindv\u00e4v som kan orsaka fibros i samband med kroniska sjukdomar. Saniona har utnyttjat sin plattform f\u00f6r l\u00e4kemedelsuppt\u00e4ckt inom jonkanaler till att precist rikta in sig mot KCa3.1. SAN903 har visat effekt i prekliniska modeller av inflammation och fibros, utan biverkningar.<\/span><\/p>\n

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STATUS F\u00d6R SAN903<\/h5>\n

Sanionas antiinflammatoriska och antifibrotiska kandidat SAN903 \u00e4r redo f\u00f6r klinisk pr\u00f6vning<\/p>\n

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V\u00c5R PIPELINE SAN903 SAN903Precis modulering av jonkanaler f\u00f6r behandling av inflammation och fibrosSAN903 \u00e4r en m\u00f6jlig first-in-class-tillg\u00e5ng som h\u00e4mmar den kalciumaktiverade kaliumjonkanalen KCa3.1. Den har genomg\u00e5tt preklinisk utveckling f\u00f6r behandling av inflammatoriska och fibrotiska sjukdomar. Den nuvarande leadindikationen \u00e4r inflammatoriska tarmsjukdomar (IBD).Hur SAN903 fungerarSAN903IMMUNCELLER OCH FIBROBLASTERINGEN produktion av cytokin\/kollagenINGEN celldelning eller migrationDen kalciumaktiverade kaliumkanalen KCa3.1 […]<\/p>\n","protected":false},"author":5,"featured_media":4139,"parent":3689,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-3707","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/saniona.com\/sv\/wp-json\/wp\/v2\/pages\/3707","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/saniona.com\/sv\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/saniona.com\/sv\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/saniona.com\/sv\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/saniona.com\/sv\/wp-json\/wp\/v2\/comments?post=3707"}],"version-history":[{"count":0,"href":"https:\/\/saniona.com\/sv\/wp-json\/wp\/v2\/pages\/3707\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/saniona.com\/sv\/wp-json\/wp\/v2\/pages\/3689"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/saniona.com\/sv\/wp-json\/wp\/v2\/media\/4139"}],"wp:attachment":[{"href":"https:\/\/saniona.com\/sv\/wp-json\/wp\/v2\/media?parent=3707"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}